Thermo Fisher Scientific SAFB Recombinant Rabbit Monoclonal Antibody (JE64-94)
SAFB 단백질을 인식하는 재조합 토끼 단클론 항체로, WB, IHC, ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. HEK293 발현 시스템 기반, Protein A 정제. 장기 보관 시 -20°C에서 냉동 보관 권장.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:5,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 | - |
| Immunocytochemistry (ICC/IF) | 1:50 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JE64-94 |
| Immunogen | Synthetic peptide within human SAFB aa 866–915 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 0.05% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2931181 |
Target Information
This gene encodes a DNA-binding protein with high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). It is involved in attaching the base of chromatin loops to the nuclear matrix. Scaffold attachment factors are a subset of nuclear matrix proteins that specifically bind to S/MAR. The encoded protein serves as a molecular base to assemble a transcriptosome complex near actively transcribed genes, regulates heat shock protein 27 transcription, acts as an estrogen receptor co-repressor, and is a candidate for breast tumorigenesis. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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