Thermo Fisher Scientific HHEX Monoclonal Antibody (1A5)
HHEX 단백질을 표적으로 하는 Mouse IgG2a 형의 단클론 항체로, Western Blot 및 ELISA에 적합합니다. 인간 시료에 반응하며, PBS 기반 액상 형태로 제공됩니다. Affinity chromatography로 정제되어 연구용으로 사용됩니다.
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- H00003087-M02
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Thermo Fisher Scientific HHEX Monoclonal Antibody (1A5)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, lambda |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1A5 |
| Immunogen | HHEX (AAH14336, 1 a.a. ~ 270 a.a) full-length recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MQYPHPGPAA GAVGVPLYAP TPLLQPAHPT PFYIEDILGR GPAAPTPAPT LPSPNSSFTS LVSPYRTPVY EPTPIHPAFS HHSAAALAAA YGPGGFGGPL YPFPRTVNDY THALLRHDPL GKPLLWSPFL QRPLHKRKGG QVRFSNDQTI ELEKKFETQK YLSPPERKRL TKMLQLSERQ VKTWFQNRRA KWRRLKQENP QSNKKEELES LDSSCDQRQD LPSEQNKGAS LDSSQCSPSP ASQEDLESEI SEDSDQEVDI EGDKSYFNAG
Target Information
HHEX is a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Expression in specific hematopoietic lineages suggests that this protein may play a role in hematopoietic differentiation.
It establishes anterior identity at two levels:
- Acts early to enhance canonical WNT-signaling by repressing expression of TLE4
- Acts later to inhibit NODAL-signaling by directly targeting NODAL.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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