ELK Biotechnology PEG3 rabbit pAb

제품명

PEG3 rabbit pAb

공급업체

ELK Biotechnology

제품 개요

PEG3 단백질을 인식하는 토끼 폴리클로날 항체로, 인간, 생쥐, 랫트에서 반응합니다. 세포 내 핵과 세포질에 존재하는 PEG3 단백질 검출에 사용됩니다.

제품 사양

Background

In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5exons and a common promoter and both genes are paternally expressed (PMID:15203203). Alternative splicing events connect their shared 5 exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3.
In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons.
Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2009]

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