ELK Biotechnology MRP-S17 rabbit pAb
인간 및 생쥐 반응성의 MRP-S17 단백질을 인식하는 토끼 폴리클로날 항체. WB, IHC, IF, ELISA에 사용 가능하며 미토콘드리아 단백질 연구에 적합. 합성 펩타이드 면역원으로 제작되어 높은 특이성과 재현성을 제공.
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제품 설명
ELK Biotechnology MRP-S17 rabbit pAb는 인간 및 생쥐의 MRP-S17 단백질을 인식하는 토끼 폴리클로날 항체입니다. 합성 펩타이드(AA 11-60)를 면역원으로 제작되었으며, 미토콘드리아 단백질 연구에 유용합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | MRP-S17 rabbit pAb |
| Alternative Names | MRPS17; RPMS17; HSPC011; 28S ribosomal protein S17; mitochondrial; MRP-S17; S17mt |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 ELISA: 1/40000 Other applications not yet tested |
| Immunogen | Synthesized peptide derived from human MRPS17 (AA range: 11–60) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 22 kDa |
| Gene ID (Human) | 51373 |
| Human Swiss-Prot No. | Q9Y2R5 |
| Cellular Localization | Mitochondrion |
| Species Reactivity | Human; Mouse |
Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and are involved in mitochondrial protein synthesis. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with approximately 75% protein to rRNA composition, unlike prokaryotic ribosomes where this ratio is reversed. Prokaryotic ribosomes contain a 5S rRNA, which is absent in mammalian mitoribosomes. The proteins comprising mitoribosomes vary significantly among species, making sequence homology recognition difficult. This gene encodes a 28S subunit protein belonging to the ribosomal protein S17P family, moderately conserved between human mitochondrial and prokaryotic ribosomal proteins. Pseudogenes corresponding to this gene are also found.
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