ELK Biotechnology MRP-S16 rabbit pAb
MRP-S16 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 적합합니다. 인간 및 생쥐 시료에 반응하며, 미토콘드리아 단백질 연구에 유용합니다. 고순도 IgG 형식으로 −20°C에서 1년간 안정 저장 가능합니다.
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제품명
MRP-S16 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | MRPS16; RPMS16; CGI-132; 28S ribosomal protein S16; mitochondrial; MRP-S16; S16mt |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000 Immunohistochemistry: 1/100–1/300 ELISA: 1/40000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MRPS16 (AA range: 81–130) |
| Host | Rabbit |
| Storage | −20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 15 kD |
| Gene ID (Human) | 51021 |
| Human Swiss-Prot No. | Q9Y3D3 |
| Cellular Localization | Mitochondrion |
| Species Reactivity | Human; Mouse |
Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and are essential for protein synthesis within mitochondria. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with approximately 75% protein to rRNA composition, contrasting with prokaryotic ribosomes where this ratio is reversed. Unlike prokaryotic ribosomes, mammalian mitoribosomes lack a 5S rRNA. The proteins comprising the mitoribosome vary significantly among species, making sequence-based identification difficult. This gene encodes a 28S subunit protein belonging to the ribosomal protein S16P family, which is highly conserved between mammalian and yeast mitochondria. Three pseudogenes are located at 8q21.3 and 20.
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