ELK Biotechnology Neurophysin I rabbit pAb
Neurophysin I 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 사용 가능. 인간 및 랫트 반응성. 합성 펩타이드(AA 40-89)로부터 면역생성. 옥시토신 전구체 연구에 적합. -20°C 보관.
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Neurophysin I rabbit pAb
제품 개요
Neurophysin I 단백질을 인식하는 토끼 폴리클로날 항체입니다. 옥시토신 및 신경분비 관련 연구에 활용되며, 다양한 응용 실험(WB, IHC, IF, ELISA)에 적합합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Neurophysin I rabbit pAb |
| Alternative Names | OXT; OT; Oxytocin-neurophysin 1; OT-NPI |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 ELISA: 1/20000 Other applications not yet tested |
| Immunogen | Synthesized peptide derived from human Neurophysin I (AA range: 40–89) |
| Host Species | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 19 kDa |
| Gene ID (Human) | 5020 |
| Human Swiss-Prot No. | P01178 |
| Cellular Localization | Secreted |
| Species Reactivity | Human; Rat |
Background
This gene encodes a precursor protein that is processed to produce oxytocin and neurophysin I. Oxytocin is a posterior pituitary hormone synthesized as an inactive precursor in the hypothalamus along with its carrier protein, neurophysin I. Together, they are packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where they are stored or secreted into the bloodstream. The precursor is activated during transport to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation and is also involved in cognition, tolerance, adaptation, complex sexual and maternal behavior, and regulation of water excretion and cardiovascular functions.
[Provided by RefSeq, Dec 2013]
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