ELK Biotechnology MOR-1 rabbit pAb
MOR-1 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 사용 가능. 인간 OPRM1 유래 펩타이드로 면역화됨. 세포막 및 수상돌기 등에서 발현. 다양한 종(Human, Rat, Mouse)에 반응.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology MOR-1 rabbit pAb
제품명
MOR-1 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | OPRM1; MOR1; Mu-type opioid receptor; M-OR-1; MOR-1; Mu opiate receptor; Mu opioid receptor; MOP; hMOP |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/40000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human OPRM1 (AA range: 21–70) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 48 kD |
| Gene ID (Human) | 4988 |
| Human Swiss-Prot No. | P35372 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein; Cell projection (axon, dendrite); Perikaryon; Endosome; Rapidly internalized after agonist binding; Isoform 12: Cytoplasm |
| Species Reactivity | Human; Rat; Mouse |
Background
This gene encodes one of at least three opioid receptors in humans, the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. It also plays a role in dependence on other drugs of abuse, such as nicotine, cocaine, and alcohol, via modulation of the dopamine system. The NM_001008503.2:c.118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity, though evidence for a causal role is conflicting. Multiple transcript variants encoding different isoforms have been identified. The canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors, while some isoforms have only 6 transmembrane domains. (RefSeq, Oct 2013)
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.