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ELK Biotechnology Trk B (phospho Tyr706) rabbit pAb
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Trk B (phospho Tyr706) rabbit pAb는 인간, 마우스, 랫트에서 반응하며 WB, IHC, IF, ELISA에 적합한 다클론 항체입니다. Tyr705 인산화 부위 펩타이드로부터 제작되었으며, 세포막 및 시냅스에서 발현되는 TrkB 단백질을 검출합니다. -20°C에서 1년 보관 가능합니다.
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- pk
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ELK Biotechnology ES6430-100UL Trk B (phospho Tyr706) rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES6430-50UL Trk B (phospho Tyr706) rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology Trk B (phospho Tyr706) rabbit pAb
제품명
Trk B (phospho Tyr706) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | NTRK2; TRKB; BDNF/NT-3 growth factors receptor; GP145-TrkB; Trk-B; Neurotrophic tyrosine kinase receptor type 2; TrkB tyrosine kinase; Tropomyosin-related kinase B |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 Immunofluorescence: 1/200 - 1/1000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Trk B around the phosphorylation site of Tyr705 (AA range: 671–720) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 92 kD |
| Gene ID (Human) | 4915 |
| Human Swiss-Prot No. | Q16620 |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein; Endosome membrane; Early endosome membrane; Cell projection (axon, dendrite); Cytoplasm (perinuclear region); Cell junction (synapse, postsynaptic density); Internalized to endosomes upon ligand-binding |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signaling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.
[Provided by RefSeq, May 2014]
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