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ELK Biotechnology IκB-β (phospho Thr19) rabbit pAb
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NF-κB 억제 단백질 IκB-β의 Thr19 인산화 형태를 인식하는 토끼 폴리클로날 항체. WB, IHC, IF, ELISA에 사용 가능하며 인간, 랫드, 마우스에 반응. 세포질 및 핵에서 발현되는 단백질 연구에 적합.
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- pk
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ELK Biotechnology ES6384-100UL IκB-β (phospho Thr19) rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES6384-50UL IκB-β (phospho Thr19) rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology IκB-β (phospho Thr19) rabbit pAb
IκB-β (phospho Thr19) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | IκB-β (phospho Thr19) rabbit pAb |
| Alternative Names | NFKBIB; IKBB; TRIP9; NF-kappa-B inhibitor beta; NF-kappa-BIB; I-kappa-B-beta; IkB-B; IkB-beta; IkappaBbeta; Thyroid receptor-interacting protein 9; TR-interacting protein 9; TRIP-9 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human IkappaB-beta around the phosphorylation site of Thr19 (AA range: 4-53) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 37 kDa |
| Gene ID (Human) | 4793 |
| Human Swiss-Prot No. | Q15653 |
| Cellular Localization | Cytoplasm, Nucleus |
| Species Reactivity | Human, Rat, Mouse |
Background
The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.
[Provided by RefSeq, Jul 2011]
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