ELK Biotechnology Myosin VA rabbit pAb
Myosin VA rabbit pAb는 인간 MYO5A 유래 펩타이드로 제작된 다클론 항체로, WB 및 IHC에 적합합니다. 세포 내 소기관과 세포골격 관련 단백질 검출에 활용되며, 인간·마우스·랫트 시료에서 반응합니다. -20°C에서 1년 보관 가능합니다.
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Myosin VA rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Myosin VA rabbit pAb |
| Alternative Names | MYO5A; MYH12; Unconventional myosin-Va; Dilute myosin heavy chain; non-muscle; Myosin heavy chain 12; Myosin-12; Myoxin |
| Applications | WB; IHC |
| Recommended Dilutions | WB 1:500–2000; IHC-p 1:50–300 |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MYO5A. AA range: 1784–1833 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 220 kD |
| GeneID (Human) | 4644 |
| Human Swiss-Prot No | Q9Y4I1 |
| Cellular Localization | Ruffle, photoreceptor outer segment, cytoplasm, lysosome, early endosome, late endosome, peroxisome, endoplasmic reticulum, Golgi apparatus, cytosol, intermediate filament, actin filament, membrane, myosin complex |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment, and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells.
Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3), and neuroectodermal melanolysosomal disease (Elejalde disease).
Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined.
[Provided by RefSeq, Dec 2008]
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