ELK Biotechnology MxB rabbit pAb
Interferon 유도 GTP 결합 단백질 MxB에 대한 rabbit polyclonal antibody로 WB 및 IHC에 적합. 인간, 랫, 마우스 반응성. 세포질 및 핵에 위치하며, GTP 결합이 핵공 복합체 국소화에 필요. -20°C에서 1년 보관 가능.
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제품명
MxB rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | MX2; Interferon-induced GTP-binding protein Mx2; Interferon-regulated resistance GTP-binding protein MxB; Myxovirus resistance protein 2; p78-related protein |
| Applications | WB; IHC |
| Recommended Dilutions | WB 1:500–2000; IHC-p 1:50–300 |
| Immunogen | Synthesized peptide derived from the internal region of human MxB |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 82 kD |
| GeneID (Human) | 4600 |
| Human Swiss-Prot No | P20592 |
| Cellular Localization | Cytoplasm; Nucleus; Nuclear pore complex (Localization to nuclear pores requires GTP-binding) |
| Species Reactivity | Human; Rat; Mouse |
Background
The protein encoded by this gene has both nuclear and cytoplasmic forms and belongs to the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino-terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not possess the antiviral activity of a similar myxovirus resistance protein 1.
[provided by RefSeq, Jul 2008]
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