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ELK Biotechnology MLK3 rabbit pAb
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ELK Biotechnology MLK3 rabbit pAb

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MLK3 단백질을 인식하는 토끼 폴리클로날 항체로, IHC, IF, ELISA에 사용 가능. 인간, 생쥐, 랫트 시료에 반응. 세포 내 JNK 신호전달 연구에 적합하며, -20°C에서 1년 보관 가능.

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pk
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ELK Biotechnology ES6252-100UL MLK3 rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES6252-50UL MLK3 rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology MLK3 rabbit pAb

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MLK3 rabbit pAb

제품 정보

항목 내용
Alternative Names MAP3K11; MLK3; PTK1; SPRK; Mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Src-homology 3 domain-containing proline-rich kinase
Applications IHC; IF; ELISA
Recommended Dilutions Immunohistochemistry: 1/100 - 1/300
ELISA: 1/20000
Not yet tested in other applications
Immunogen The antiserum was produced against synthesized peptide derived from human MLK3. AA range: 640-689
Host Rabbit
Storage -20°C / 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Gene ID (Human) 4296
Human Swiss-Prot No. Q16584
Cellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Location is cell cycle dependent.
Species Reactivity Human; Mouse; Rat

Background

The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. It preferentially activates MAPK8/JNK kinase and functions as a positive regulator of the JNK signaling pathway. MLK3 can directly phosphorylate and activate IkappaB kinase alpha and beta, and is involved in the transcriptional activity of NF-kappaB mediated by Rho family GTPases and CDC42.
[provided by RefSeq, Jul 2008]

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