ELK Biotechnology MIC2 rabbit pAb
Human CD99(MIC2) 단백질을 인식하는 rabbit polyclonal antibody로, IF, IHC, ELISA에 적합합니다. 세포막 단백질 검출에 사용되며, T-cell 관련 연구 및 암 억제 단백질 분석에 활용 가능합니다. -20°C에서 1년 보관 가능합니다.
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제품명
MIC2 rabbit pAb
공급업체
ELK Biotechnology
제품 개요
MIC2(CD99) 단백질을 인식하는 rabbit polyclonal antibody입니다. 세포막 단백질 검출 및 T-cell 관련 연구에 적합하며, 다양한 실험 응용 분야에서 활용 가능합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | CD99; MIC2; MIC2X; MIC2Y; CD99 antigen; 12E7; E2 antigen; Protein MIC2; T-cell surface glycoprotein E2; CD antigen CD99 |
| Applications | IF; IHC; ELISA |
| Recommended Dilutions | Immunofluorescence: 1/200 - 1/1000 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CD99 (AA range: 11–60) |
| Species Reactivity | Human; Rat; Mouse |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| GeneID (Human) | 4267 |
| Human Swiss-Prot No | P14209 |
| Cellular Localization | Membrane; Single-pass type I membrane protein |
배경 (Background)
The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. There is a related pseudogene located immediately adjacent to this locus. (RefSeq, Mar 2016)
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