ELK Biotechnology Histamine H1 Receptor (phospho Ser398) rabbit pAb
Histamine H1 Receptor (phospho Ser398) rabbit pAb는 인산화된 Ser398 부위를 인식하는 항체로, IF 및 ELISA에 적합합니다. 사람, 생쥐, 랫드에 반응하며 세포막 단백질 검출에 유용합니다. 폴리클로날 IgG 형태로 -20°C에서 1년간 보관 가능합니다.
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Histamine H1 Receptor (phospho Ser398) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Histamine H1 Receptor (phospho Ser398) rabbit pAb |
| Alternative Names | HRH1; Histamine H1 receptor; H1R; HH1R |
| Applications | IF; ELISA |
| Recommended Dilutions | Immunofluorescence: 1/200 - 1/1000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against a synthesized peptide derived from human Histamine H1 Receptor around the phosphorylation site of Ser398 (AA range: 364–413) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 3269 |
| Human Swiss-Prot No | P35367 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein |
| Species Reactivity | Human; Mouse; Rat |
Background
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3, and H4.
The protein encoded by this gene is an integral membrane protein belonging to the G protein-coupled receptor superfamily.
It mediates smooth muscle contraction, increased capillary permeability, catecholamine release from the adrenal medulla, and neurotransmission in the central nervous system.
This receptor is associated with processes such as memory, learning, circadian rhythm, and thermoregulation, and contributes to allergic diseases including atopic dermatitis, asthma, anaphylaxis, and allergic rhinitis.
Multiple alternatively spliced variants encoding the same protein have been identified.
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