ELK Biotechnology MGST1 rabbit pAb
MGST1 단백질을 인식하는 토끼 폴리클로날 항체로, WB와 IHC에 적합합니다. 인간 유래 합성 펩타이드로 면역화되었으며, 세포 내 미세소체 및 미토콘드리아 외막에 위치한 단백질 검출에 유용합니다. 장기 보관은 -20°C에서 가능합니다.
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제품명
MGST1 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | MGST1; GST12; MGST; Microsomal glutathione S-transferase 1; Microsomal GST-1; Microsomal GST-I |
| Applications | WB; IHC |
| Recommended Dilutions | WB 1:500–2000; IHC-p 1:50–300 |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MGST1. AA range: 42–91 |
| Host Species | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 18 kDa |
| Gene ID (Human) | 4257 |
| Human Swiss-Prot No. | P10620 |
| Cellular Localization | Microsome; Mitochondrion outer membrane; Peripheral membrane protein; Endoplasmic reticulum membrane; Multi-pass membrane protein |
| Species Reactivity | Human; Mouse |
Background
The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds.
This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress. Several transcript variants, some non-protein coding and some protein coding, have been found for this gene. [provided by RefSeq, May 2012]
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