ELK Biotechnology MEF-2D (phospho Ser444) rabbit pAb
MEF-2D (phospho Ser444) rabbit pAb는 MEF2D 단백질의 Ser444 인산화 부위를 인식하는 폴리클로날 항체입니다. WB, IHC, IF, ELISA에 사용 가능하며, 인간, 마우스, 랫트 시료에 반응합니다. 근육 및 신경 세포 분화 연구에 적합합니다.
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MEF-2D (phospho Ser444) rabbit pAb
공급업체: ELK Biotechnology
제품명: MEF-2D (phospho Ser444) rabbit pAb
대체명: MEF2D; Myocyte-specific enhancer factor 2D
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000 Immunohistochemistry: 1/100–1/300 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human MEF2D around phosphorylation site of Ser444 (AA range: 410–459) |
| Host | Rabbit |
| Storage | -20 °C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 55 kD |
| GeneID (Human) | 4209 |
| Human Swiss-Prot No | Q14814 |
| Cellular Localization | Nucleus. Translocated by HDAC4 to nuclear dots. |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene belongs to the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family regulate muscle and neuronal cell differentiation and development, and are modulated by class II histone deacetylases. Fusions of MEF2D with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) have been identified in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The protein may also be involved in Parkinson’s disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants.
[provided by RefSeq, Oct 2012]
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