ELK Biotechnology MEF-2C (phospho Ser387) rabbit pAb
MEF-2C (phospho Ser387) rabbit pAb는 인산화된 MEF2C 단백질을 특이적으로 인식하는 폴리클로날 항체입니다. IHC, IF, ELISA에 사용 가능하며, 근육세포 분화 및 신경 발달 연구에 적합합니다. 인간 및 마우스 시료에 반응합니다.
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제품명
MEF-2C (phospho Ser387) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | MEF2C; Myocyte-specific enhancer factor 2C |
| Applications | IHC; IF; ELISA |
| Recommended Dilutions | Immunohistochemistry: 1/100 - 1/300 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human MEF2C around the phosphorylation site of Ser387 (AA range: 353–402) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Gene ID (Human) | 4208 |
| Human Swiss-Prot No. | Q06413 |
| Cellular Localization | Nucleus; Cytoplasm, sarcoplasm |
| Species Reactivity | Human; Mouse |
Background
This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe mental retardation, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described.
[provided by RefSeq, Jul 2010]
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