ELK Biotechnology MAP-4 rabbit pAb
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| Product name: | MAP-4 rabbit pAb |
| Alternative Names: | MAP4; Microtubule-associated protein 4; MAP-4 |
| Applications: | IHC;IF;ELISA |
| Recommended Dilutions: | Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human MAP4. AA range:662-711 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| GeneID（Human）: | 4134 |
| Human Swiss-Prot No: | P27816 |
| Cellular localization: | Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, microtubule organizing center . Recruitment to microtubule is inhibited by microtubules polyglutamylation. . |
| Background: | The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008], |
| Species Reactivity: | Human;Mouse;Rat |
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