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ELK Biotechnology MARCKS (phospho Ser159) rabbit pAb
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MARCKS 단백질의 인산화형(Ser159)을 인식하는 토끼 폴리클로날 항체. Western blot 및 ELISA에 적합하며, 세포골격 및 막 관련 단백질 연구에 활용 가능. 인간, 생쥐, 랫트 반응성. -20°C에서 1년 보관 가능.
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- pk
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ELK Biotechnology ES6149-100UL MARCKS (phospho Ser159) rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES6149-50UL MARCKS (phospho Ser159) rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology MARCKS (phospho Ser159) rabbit pAb
제품명
MARCKS (phospho Ser159) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | MARCKS; MACS; PRKCSL; Myristoylated alanine-rich C-kinase substrate; Protein kinase C substrate; 80 kDa protein, light chain; 80K-L protein; PKCSL |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/20000 Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MARCKS around the phosphorylation site of Ser158. AA range: 126-175 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 35 kDa |
| Gene ID (Human) | 4082 |
| Human Swiss-Prot No. | P29966 |
| Cellular Localization | Cytoplasm, cytoskeleton; Membrane; Lipid-anchor |
| Species Reactivity | Human; Mouse; Rat |
Background
The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and functions as an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its relocation to the cytoplasm. This protein is involved in cell motility, phagocytosis, membrane trafficking, and mitogenesis.
[Provided by RefSeq, Jul 2008]
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