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ELK Biotechnology Rho GDIα (phospho Ser174) rabbit pAb
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Rho GDIα 단백질의 Ser174 인산화 부위를 인식하는 rabbit polyclonal antibody. WB, IHC, IF, ELISA에 적합하며 세포 내 Rho GTPase 신호 조절 연구에 활용 가능. Human, Mouse, Rat 시료에 반응.
- 판매단위
- pk
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ELK Biotechnology ES6106-100UL Rho GDIα (phospho Ser174) rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES6106-50UL Rho GDIα (phospho Ser174) rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology Rho GDIα (phospho Ser174) rabbit pAb
Rho GDIα (phospho Ser174) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Rho GDIα (phospho Ser174) rabbit pAb |
| Alternative Names | ARHGDIA; GDIA1; Rho GDP-dissociation inhibitor 1; Rho GDI 1; Rho-GDI alpha |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human ARHGDIA around the phosphorylation site of Ser174 (AA range: 140–189) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 23 kDa |
| Gene ID (Human) | 396 |
| Human Swiss-Prot No. | P52565 |
| Cellular Localization | Cytoplasm |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the dissociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants.
[Provided by RefSeq, Jul 2014]
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