ELK Biotechnology Lck (phospho Ser540) rabbit pAb
Lck 단백질의 Ser540 인산화 부위를 인식하는 토끼 폴리클로날 항체. WB 및 ELISA에 적합하며 인간, 마우스, 랫트 시료에서 반응. 세포막 및 세포질 내 Lck 신호전달 연구에 활용 가능. -20°C에서 1년 보관.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology Lck (phospho Ser540) rabbit pAb
제품명
Lck (phospho Ser540) rabbit pAb
제품 개요
Lck 단백질의 Ser540 인산화 부위를 특이적으로 인식하는 토끼 폴리클로날 항체입니다. T세포 발달 및 신호전달 연구에 활용됩니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | LCK; Tyrosine-protein kinase Lck; Leukocyte C-terminal Src kinase; LSK; Lymphocyte cell-specific protein-tyrosine kinase; Protein YT16; Proto-oncogene Lck; T cell-specific protein-tyrosine kinase; p56-LCK |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000, ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human LCK around the phosphorylation site of Ser59. AA range: 26–75 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 58 kD |
| Gene ID (Human) | 3932 |
| Human Swiss-Prot No. | P06239 |
| Cellular Localization | Cell membrane; Lipid-anchor; Cytoplasmic side; Cytoplasm, cytosol. Present in lipid rafts in an inactive form. |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Aug 2016]
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.