ELK Biotechnology Laminin β-2 rabbit pAb
Laminin β-2 rabbit polyclonal antibody for WB, IHC, IF, ELISA applications. Recognizes human LAMB2 peptide (AA 61–110). Useful for studying extracellular matrix and basement membrane proteins. High specificity and stability with 1 mg/ml concentration.
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Laminin β-2 rabbit pAb
Supplier: ELK Biotechnology
제품 정보
| 항목 | 내용 |
|---|---|
| Product Name | Laminin β-2 rabbit pAb |
| Alternative Names | LAMB2; LAMS; Laminin subunit beta-2; Laminin B1s chain; Laminin-11 subunit beta; Laminin-14 subunit beta; Laminin-15 subunit beta; Laminin-3 subunit beta; Laminin-4 subunit beta; Laminin-7 subunit beta; Laminin-9 subunit beta; S-laminin sub |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000 Immunohistochemistry: 1/100–1/300 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human LAMB2 (AA range: 61–110) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 210 kD |
| GeneID (Human) | 3913 |
| Human Swiss-Prot No | P55268 |
| Species Reactivity | Human; Mouse; Rat |
| Cellular Localization | Secreted; extracellular space; extracellular matrix; basement membrane. S-laminin is concentrated in the synaptic cleft of the neuromuscular junction. |
Background
Laminins are extracellular matrix glycoproteins and major non-collagenous components of basement membranes. They play roles in cell adhesion, differentiation, migration, signaling, neurite outgrowth, and metastasis. Laminins consist of three non-identical chains—alpha, beta, and gamma—forming a cruciform structure with three short arms and one long arm. Each chain is encoded by a distinct gene, and multiple isoforms exist. Different combinations of alpha, beta, and gamma chains form heterotrimeric laminin isoforms, designated by Arabic numerals according to their discovery (e.g., α1β1γ1 = laminin 1).
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