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ELK Biotechnology c-Kit rabbit pAb
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c-Kit 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 사용 가능. 인간 및 생쥐 시료에 반응하며, 세포막 및 세포질 내 발현 단백질 검출에 적합. -20°C에서 1년 보관 가능.
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- pk
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ELK Biotechnology ES6023-100UL c-Kit rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES6023-50UL c-Kit rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology c-Kit rabbit pAb
ELK Biotechnology c-Kit rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | c-Kit rabbit pAb |
| Alternative Names | KIT; SCFR; Mast/stem cell growth factor receptor Kit; SCFR; Piebald trait protein; PBT; Proto-oncogene c-Kit; Tyrosine-protein kinase Kit; p145 c-kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD antigen CD117 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human KIT (AA range: 906–955) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 117 kD |
| GeneID (Human) | 3815 |
| Human Swiss-Prot No. | P10721 |
| Species Reactivity | Human; Mouse |
| Cellular Localization | Isoform 1: Cell membrane (Single-pass type I membrane protein) Isoform 2: Cell membrane (Single-pass type I membrane protein) Isoform 3: Cytoplasm (Detected in cytoplasm of spermatozoa, especially in the equatorial and subacrosomal region of the sperm head) |
Background
This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been identified.
[provided by RefSeq, Jul 2008]
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