Thermo Fisher Scientific CDH17 Recombinant Rabbit Monoclonal Antibody (029)

Applications and Tested Dilutions

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.

Advantages of recombinant rabbit monoclonal antibodies:

• High specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity to diverse targets due to larger rabbit immune repertoire

This antibody has specificity for Human Cadherin-17/LI-cadherin/CDH17.

Target Information

The CDH17 gene belongs to the cadherin superfamily, encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region with seven cadherin domains and a transmembrane region but lacking the conserved cytoplasmic domain.

CDH17 is expressed in the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter involved in the absorption of peptide-based drugs. It may also play a role in the morphological organization of the liver and intestine. Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.