Thermo Fisher Scientific Contactin 2 Recombinant Rabbit Monoclonal Antibody (4V7O8)

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000–1:20,000

ELISA

• Tested Concentration: 1 µg/mL

Product Specifications

Product Specific Information

Immunogen Sequence:

SQTTFGPVFE DQPLSVLFPE ESTEEQVLLA CRARASPPAT YRWKMNGTEM KLEPGSRHQL VGGNLVIMNP TKAQDAGVYQ CLASNPVGTV VSREAILRFG FLQEFSKEER DPVKAHEGWG VMLPCNPPAH YPGLSYRWLL NEFPNFIPTD GRHFVSQTTG NLYIARTNAS DLGNYSCLAT SHMDFSTKSV FSKFAQLNLA AEDTRLFAPS IKARFPAETY ALVGQQVTLE CFAFGNPVPR IKWRKVDGSL SPQWTTAEPT LQIPSVSFED EGTYECEAEN SKGRDTVQGR IIVQAQPEWL KVISDTEADI GSNLRWGCAA AGKPRPTVRW LRNGEPLASQ NRVEVLAGDL RFSKLSLEDS GMYQCVAENK HGTIYASAEL AVQALAPDFR LNPVRRLIPA ARGGEILIPC QPRAAPKAVV LWSKGTEILV NSSRVTVTPD GTLIIRNISR SDEGKYTCFA ENFMGKANST GILSVRDATK ITLAPSSADI NLGDNLTLQC HASHDPTMDL TFTWTLDDFP IDFDKPGGHY RRTNVKETIG DLTILNAQLR HGGKYTCMAQ TVVDSASKEA TVLVRGPPGP PGGVVVRDIG DTTIQLSWSR GFDNHSPIAK YTLQARTPPA GKWKQVRTNP ANIEGNAETA QVLGLTPWMD YEFRVIASNI LGTGEPSGPS SKIRTREAAP SVAPSGLSGG GGAPGELIVN WTPMSREYQN GDGFGYLLSF RRQGSTHWQT ARVPGADAQY FVYSNESVRP YTPFEVKIRS YNRRGDGPES LTALVYSAEE EPRVAPTKVW AKGVSSSEMN VTWEPVQQDM NGILLGYEIR YWKAGDKEAA ADRVRTAGLD TSARVSGLHP NTKYHVTVRA YNRAGTGPAS PSANATTMKP PPRRPPGNIS WTFSSSSLSI KWDPVVPFRN ESAVTGYKML YQNDLHLTPT LHLTGKNWIE IPVPEDIGHA LVQIRTTGPG GDGIPAEVHI VRNGGTSMMV EN

Target Information

Contactin 2 (CNTN2, also known as transiently-expressed axonal glycoprotein, AXT, TAX, TAX1, TAG-1, axonin 1)
Contactin 2 is a neuronal cell adhesion molecule (CAM) that influences axon connection formation during nervous system development. It belongs to the immunoglobulin superfamily (IgSF) and contains a GPI-anchor, six Ig-like, and four Fibronectin type III (FNIII)-like domains.
Expressed predominantly during neural development on axonal membranes, it guides commissural axons without promoting growth.
Contactin 2 binds with NgCAM in the same membrane (cis-binding). Heterophilic binding (Contactin 2/NgCAM and Contactin 2/NrCAM) occurs in the first four Ig domains, while homophilic binding (Contactin 2/Contactin 2) occurs in the FNIII domain.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.