Thermo Fisher Scientific FMRP Monoclonal Antibody (6A15)

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

Immunocytochemistry (ICC/IF)

Assay-dependent

-

ELISA (ELISA)

Assay-dependent

-

Immunoprecipitation (IP)

25 µg/mL

-

Product Specifications

Species Reactivity

Fruit fly

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

6A15

Immunogen

His-dFMR1 fusion protein (Drosophila melanogaster) (C-terminal 580aa) (aa 580-684). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FMRP,uniProtId:Q9NFU0-1,ncbiNodeId:7227,antigenRange:580-684,antigenLength:684,antigenImageFileName:MA5-36292_FMRP_Q9NFU0-1_House_mouse.svg,antigenImageFileNamePDP:MA5-36292_FMRP_Q9NFU0-1_House_mouse_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2896814

Product Specific Information

MA1-5771 detects FMR1 in drosophila samples (does not cross react with human). Western blot detects a band of approximately 85kDa (predicted molecular weight: 82kDa).

Target Information

FMR1 binds RNA and is associated with polysomes. The protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat in the 5` UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure. Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.