Thermo Fisher Scientific FMRP Monoclonal Antibody (6A15)
FMRP 단백질을 인식하는 Mouse monoclonal antibody로 Drosophila 시료에 특이적입니다. Western blot, ICC/IF, ELISA, IP 등 다양한 응용에 적합하며, Protein A로 정제된 액상 형태입니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | 25 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Fruit fly |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6A15 |
| Immunogen | His-dFMR1 fusion protein (Drosophila melanogaster) (C-terminal 580aa, aa 580–684) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2896814 |
Product Specific Information
MA1-5771 detects FMR1 in Drosophila samples and does not cross-react with human.
Western blot detects a band of approximately 85 kDa (predicted molecular weight: 82 kDa).
Target Information
FMR1 binds RNA and is associated with polysomes. The protein may be involved in mRNA trafficking from the nucleus to the cytoplasm.
A trinucleotide repeat in the 5' UTR is normally found at 6–53 copies, but an expansion to 55–230 repeats causes fragile X syndrome.
Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure.
Multiple alternatively spliced transcript variants encoding different protein isoforms located in different cellular compartments have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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