Thermo Fisher Scientific RFXAP Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.2–1.0 µg/mL

Product Specifications

Product Specific Information

This target displays homology in the following species:
Cow: 79%; Dog: 79%; Guinea Pig: 86%; Horse: 79%; Human: 79%; Mouse: 100%; Rabbit: 79%; Rat: 93%

Target Information

Major histocompatibility (MHC) class II molecules are transmembrane proteins that play a central role in the development and control of the immune system.
The protein encoded by this gene, together with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription.
Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression.
Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D.
Transcript variants utilizing different polyA signals have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.