Thermo Fisher Scientific TIMP3 Polyclonal Antibody
TIMP3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot 및 Immunocytochemistry에 적합합니다. 인간, 마우스, 랫트 반응성이 있으며, 액상 형태로 제공됩니다. Affinity chromatography로 정제되었으며, PBS와 50% glycerol buffer에 보관됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TIMP3 (Accession P35625), corresponding to amino acid residues I147–G197 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2900682 |
Product Specific Information
Antibody detects endogenous levels of total TIMP3.
Target Information
Tissue inhibitor of metalloproteinase 3 (TIMP3) is a member of the tissue inhibitor of metalloproteinases gene family. It functions to inhibit the activity of matrix metalloproteinases (MMP), which degrade components of the extracellular matrix. TIMP3 is expressed upon mitogenic stimulation and binds irreversibly to zinc-dependent MMPs, inactivating them by binding to their catalytic zinc cofactor. Other functions of TIMP3 include roles in nervous system development, tissue regeneration, and visual perception. In humans, the gene encoding TIMP3 is located on chromosome 22.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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