Thermo Fisher Scientific Diazepam Binding Inhibitor Polyclonal Antibody
Rabbit 폴리클로날 항체로 인간 Diazepam Binding Inhibitor를 인식합니다. Western blot 및 Immunoprecipitation에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol 완충액에 보관되며 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunoprecipitation (IP)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human Diazepam Binding Inhibitor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720456 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% (by SDS-PAGE).
Target Information
This gene encodes diazepam binding inhibitor, a protein regulated by hormones and involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors in brain synapses.
The protein is conserved from yeast to mammals, with a highly conserved domain consisting of seven contiguous residues that form the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters.
Diazepam binding inhibitor mediates feedback regulation of pancreatic secretion and postprandial release of cholecystokinin, and acts as a mediator in corticotropin-dependent adrenal steroidogenesis.
Three pseudogenes located on chromosomes 6, 8, and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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