Thermo Fisher Scientific NFX1 Polyclonal Antibody
NFX1 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 적합. 4°C 보관, 1년의 권장 보관 기간. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
- Publications: [참조 없음]
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
- Publications: [참조 없음]
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1070 and 1120 of human Nuclear Transcription Factor, X-box Binding 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
Target Information
MHC class II gene expression is primarily regulated at the transcriptional level by transcription factors binding to conserved X and Y boxes in the proximal promoter region.
NFX1 acts as a transcriptional repressor binding to the X box motif of HLA-DRA and other MHC class II genes in vitro.
It may regulate the duration of inflammatory responses by limiting the period during which class II MHC molecules are induced by IFN-gamma.
Three alternative splice variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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