Thermo Fisher Scientific NFX1 Polyclonal Antibody

Applications

• Western Blot (WB): Assay-dependent
• Immunoprecipitation (IP): 2–5 µg/mg lysate

Product Specifications

Product Specific Information

The recommended shelf life for this product is 1 year from date of receipt.

Target Information

MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes.
NFX1 is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma.
Three alternative splice variants, each of which encodes a different isoform, have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.