Thermo Fisher Scientific FAM131C Monoclonal Antibody (OTI6E2), TrueMAB
FAM131C 단백질을 인식하는 Mouse monoclonal antibody로 Western blot 및 IHC(P) 검증 완료. 인간 시료에 반응하며, Affinity chromatography로 정제된 액상 형태. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6E2 |
| Immunogen | Full length human recombinant protein of human FAM131C produced in E.coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The F131C gene encodes a member of the superoxide dismutase (SOD) protein family.
SODs are antioxidant enzymes that catalyze the conversion of superoxide radicals into hydrogen peroxide and oxygen, which may protect the brain, lungs, and other tissues from oxidative stress.
Proteolytic processing of the encoded protein results in the formation of two distinct homotetramers that differ in their ability to interact with the extracellular matrix (ECM).
Homotetramers consisting of the intact protein (type C subunit) exhibit high affinity for heparin and are anchored to the ECM, whereas homotetramers consisting of a proteolytically cleaved form (type A subunit) show low affinity for heparin and do not interact with the ECM.
A mutation in this gene may be associated with increased heart disease risk.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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