Thermo Fisher Scientific Chromogranin A/CHGA Recombinant Mouse Monoclonal Antibody (rCHGA, 413)
인간 CHGA 단백질을 인식하는 재조합 마우스 단클론 항체로, 신경내분비 종양 연구에 적합합니다. IHC(P)와 Peptide Array에 사용 가능하며, Rat에는 반응하지 않습니다. Protein A/G로 정제된 액상 형태로 4°C 보관합니다.
- 카탈로그번호
- 1113-MSM18-P0
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 0.25–0.5 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | rCHGA, 413 |
| Immunogen | Recombinant full-length human CHGA protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- This antibody does not react with Rat.
- For Immunohistochemistry (PFA fixed): incubate antibody for 30 min at room temperature.
- For formalin-fixed tissues: heat tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, then cool at room temperature for 20 min.
Target Information
Chromogranin A (CHGA) is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is located in secretory vesicles of neurons and endocrine cells. CHGA serves as a precursor to three biologically active peptides—vasostatin, pancreastatin, and parastatin—which act as autocrine or paracrine negative modulators of the neuroendocrine system.
CHGA is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Coexpression of chromogranin A and neuron-specific enolase (NSE) is common in neuroendocrine neoplasms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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