Thermo Fisher Scientific Caspase 1 Polyclonal Antibody
Thermo Fisher Scientific Caspase 1 Polyclonal Antibody는 인간 Caspase-1 단백질을 표적하는 Rabbit IgG 항체로, WB, IHC, ICC 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 1 publication |
| Immunohistochemistry (IHC) | – | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | View publications |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 129–393 of Human Caspase 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546818 |
Product Specific Information
- Recommended positive control: A549
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
Caspases are a family of cysteine proteases divided into apoptotic and inflammatory subfamilies. Inflammatory caspases, including caspase-1, -4, -5, and -12, are associated with immune responses to microbial pathogens rather than cell death. Caspase-1 activates proinflammatory cytokines such as IL-1β and IL-18. It was initially identified as an IL-1β-converting enzyme and later found to be a mammalian homolog of the C. elegans cell death gene ced-3, whose overexpression can induce apoptosis in fibroblasts.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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