Thermo Fisher Scientific Acid Phosphatase 1 Polyclonal Antibody
Thermo Fisher Scientific의 Acid Phosphatase 1 폴리클로날 항체는 인간 ACP1 단백질을 인식하며 WB, IHC, ICC, Flow Cytometry 등 다양한 응용에 적합합니다. Rabbit IgG 기반으로 제작되었으며, 높은 특이성과 안정성을 제공합니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:10–1:50 |
| Flow Cytometry (Flow) | 1:10–1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 33–61 amino acids from the N-terminal region of human ACP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2543918 |
Target Information
Low molecular weight protein tyrosine phosphatases, including the human red cell phosphatase HCPTP, are widely expressed cytosolic proteins of approximately 18 kDa that exist in distinct isoforms. These enzymes are highly selective for phosphotyrosine and are sensitive to inhibition by vanadate. The catalytic mechanism involves formation of a cystinylphosphate intermediate. The crystal structure of the bovine heart-derived enzyme (BHPTP) shows a four-stranded central parallel β-sheet with flanking α-helices and an active site cysteine residue in the typical tyrosine phosphatase sequence context, CXXXXXR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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