Thermo Fisher Scientific KPNB1 Monoclonal Antibody (OTI10D3), TrueMAB
인간 KPNB1 단백질을 인식하는 마우스 모노클로날 항체로, Western blot에 적합합니다. 1 mg/mL 농도의 액상 제품이며, PBS/BSA/glycerol 완충액에 보존됩니다. 친화 크로마토그래피로 정제되었으며, -20°C에서 보관합니다.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10D3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–200 of human KPNB1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Nucleocytoplasmic transport is a signal- and energy-dependent process occurring through nuclear pore complexes in the nuclear envelope. Proteins containing a nuclear localization signal (NLS) require the import receptor complex composed of importin alpha and beta subunits (karyopherins). Importin alpha binds the NLS-containing cargo, while importin beta mediates docking at the nuclear pore. In the presence of nucleoside triphosphates and Ran GTPase, the complex translocates into the nucleus, where importin subunits dissociate. Importin alpha delivers the cargo into the nucleoplasm, and importin beta remains at the pore. Interactions between importin beta and nucleoporins' FG repeats are essential for translocation. The encoded protein is a member of the importin beta family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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