Thermo Fisher Scientific DTX3L Polyclonal Antibody
DTX3L 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 최적화되어 있으며 인간에 반응하고, 원숭이·소·돼지·고양이에 교차 반응 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 안정성을 제공.
- 카탈로그번호
- 720394
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 2.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide corresponding to human DTX3L (aa709–aa728, aa194–aa213) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.1% BSA, 30% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723101 |
Product Specific Information
This antibody is predicted to react with Monkey, Bovine, Pig, Cat.
Target Information
Component of the shelterin complex (telosome) involved in regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity, telomeres are exposed to DNA damage surveillance and processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA and modulates inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity. May play a role in organogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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