Thermo Fisher Scientific Histone H1T Polyclonal Antibody
Rabbit polyclonal antibody targeting human Histone H1T. Validated for IHC (Paraffin) with high specificity. Purified via antigen affinity chromatography and supplied in PBS with glycerol. Suitable for chromatin structure and histone research applications.
- 카탈로그번호
- PA566983
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- pk
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:1,000–1:2,500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human Histone H1T. Recombinant protein control fragment (Product #RP-107626) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662686 |
Product Specific Information
- Immunogen sequence:
SETVPAASASA GVAAMEKLPT KKRGRKPAGL ISASRKVPNL SVSKLITEAL SVSQERVGMS - Ortholog sequence identity: Mouse 55%, Rat 57%
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes and contributes to chromatin compaction into higher-order structures.
This gene is intronless and encodes a replication-dependent histone that belongs to the histone H4 family. Transcripts from this gene lack polyA tails but contain a palindromic termination element.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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