Thermo Fisher Scientific TRAF2 Polyclonal Antibody
TRAF2 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 Immunoprecipitation에 적합. 인간 TNF receptor-associated factor 2의 175~225번 잔기 영역을 면역원으로 사용. 4°C 보관, 1년 권장 보관기간.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 175 and 225 of Human TNF receptor-associated factor 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
Tumor necrosis factor (TNF) receptor-associated factors (TRAFs) act as adaptor proteins linking the TNF receptor superfamily to signaling pathways, playing key roles in regulating cell death and stress responses.
TRAF proteins share a homology region that facilitates binding to cell receptors and other TRAF proteins, activating various signaling cascades.
TRAF2 and TRAF3 directly bind to CD40, an NF receptor superfamily member, and are essential for NF-kappa-B activation in mouse B lymphocytes.
TRAF2, together with TRAF6, is required for CD40 signaling in non-hematopoietic cells and interacts with lymphotoxin-beta receptor (LTbetaR) along with TRAF3 and apoptosis inhibitors cIAP1 and Smac.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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