Thermo Fisher Scientific PSMA8 Monoclonal Antibody (21D11)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

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Immunohistochemistry (IHC)

-

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ELISA (ELISA)

1.0-5 µg/mL

-

Immunoprecipitation (IP)

5-10 µg

-

Miscellaneous PubMed (Misc)

-

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Product Specifications

Published species

Human, Mouse

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

21D11

Immunogen

Cellular Proteosome fraction containing multiple á subunits, prepared from bovine cells.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2533064

Target Information

Component of the spermatoproteasome, a proteasome specifically found in testis that promotes acetylation-dependent degradation of histones, thereby participating actively to the exchange of histones during spermatogenesis. The proteasome is a protein complexe that degrades unneeded or damaged proteins by proteolysis, a chemical reaction that breaks peptide bonds. Required for 20S core proteasome assembly, essential for the degradation of meiotic proteins RAD51 and RPA1 at late prophase I and the progression of meiosis I during spermatogenesis. Localizes to the synaptonemal complex, a zipper-like structure that holds homologous chromosome pairs in synapsis during meiotic prophase I. [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.