Thermo Fisher Scientific FGF23 (Fibroblast Growth Factor 23) Monoclonal Antibody (FGF23, 4166)
FGF23 단백질을 인식하는 마우스 단클론 항체로, 인간 시료에 반응합니다. IHC(P) 및 Peptide Array에 사용 가능하며, PBS(pH 7.4) 용액 형태로 제공됩니다. 단백질 A/G로 정제되었으며, 보존제가 포함되지 않습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | FGF23, 4166 |
| Immunogen | Recombinant fragment (around aa25–251) of human FGF23 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | –20°C or –80°C (preferred) |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed):
Incubate antibody for 30 minutes at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
The protein encoded by this gene belongs to the fibroblast growth factor (FGF) family, which has broad mitogenic and cell survival activities. FGF family members are involved in embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion.
FGF23 inhibits renal tubular phosphate transport. Mutations in this gene are associated with autosomal dominant hypophosphatemic rickets and familial tumoral calcinosis with hyperphosphatemia. Elevated FGF23 expression has been observed in oncogenic hypophosphatemic osteomalacia, a disorder of phosphate metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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