Thermo Fisher Scientific ESAM Polyclonal Antibody
Human ESAM 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:500~1:2,000 희석으로 사용 가능. 보존제가 없는 액상 형태이며, Protein A 및 항원 친화 크로마토그래피로 정제됨. 혈관 투과성 조절 연구에 적합.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the C-terminus of the Human Endothelial Cell Adhesion Molecule |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787897 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human Endothelial Cell Adhesion Molecule.
Target Information
ESAM is a 55-kDa membrane protein composed of two extracellular Ig domains, a single transmembrane domain, and a 120 amino acid cytoplasmic domain.
It is related to members of the junctional adhesion molecule (JAM) family and is expressed on endothelial cells and activated platelets.
ESAM at endothelial tight junctions plays a role in regulating vascular permeability in response to agents such as VEGF or extravasating neutrophils.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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