Thermo Fisher Scientific MEK2 Polyclonal Antibody
Human MEK2 단백질을 인식하는 Goat Polyclonal Antibody로, Western blot에 최적화되어 있습니다. 0.1–0.3 µg/mL 희석 권장, 비결합형 액상 형태이며 0.5 mg/mL 농도. -20°C 보관, 연구용 전용 제품입니다.
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Applications and Tested Dilution
- Application: Western Blot (WB)
- Tested Dilution: 0.1–0.3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-DLKMLTNHTFIKRS (aa 359–372) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933753 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
MAP2K2 (MEK2) is a dual specificity serine/threonine kinase that plays a critical role in mitogen growth factor signal transduction.
Mitogen-activated protein kinase 2 (MEK2 or MAPKK2) belongs to a family of tyrosine/threonine protein kinases that activate ERK1/2 and MAPK enzymes by phosphorylating residues within the TEY motif in the activation loop.
MEK1 and MEK2 are activated by dual phosphorylation on serine 218 and 222. Threonine 292 of MEK1 is phosphorylated by ERK2, providing a negative feedback regulation mechanism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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