Thermo Fisher Scientific SR-BI Polyclonal Antibody
SR-BI 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체입니다. Western blot 및 파라핀 조직 IHC에 적합하며, 인간 시료에 반응합니다. 고순도 정제, 안정적인 액상 형태로 제공되며 연구용으로 사용됩니다.
- 카탈로그번호
- PA5143115
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.01–0.03 µg/mL
- Publications: References
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 5 µg/mL
- Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-TSAPKGSVLQEAK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933754 |
Product Specific Information
- This antibody is expected to recognize isoform 1 (NP_005496.4) only.
- Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
High density lipoproteins (HDLs) play a critical role in cholesterol metabolism, and their plasma concentrations are inversely correlated with the risk for atherosclerosis.
SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester.
It is expressed primarily in liver and nonplacental steroidogenic tissues and mediates selective cholesterol uptake by a distinct mechanism.
In mice, SR-BI plays a key role in determining plasma lipoprotein cholesterol levels and cholesterol storage in the adrenal gland.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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