Thermo Fisher Scientific TTK Polyclonal Antibody
TTK 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합. Human, Mouse, Rat 반응성. 고순도 Affinity Chromatography 정제 제품으로, 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TTK (Accession P33981), corresponding to amino acid residues P650–S700 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854577 |
Product Specific Information
Antibody detects endogenous levels of total TTK.
Target Information
TTK is a serine/threonine kinase closely related to SPK1, PIM1, and CDC2 kinases. It is a dual-specificity kinase capable of phosphorylating tyrosine residues. The enzyme consists of a catalytic subunit and a constant regulatory subunit that associates with various regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule coordinating the assembly of the catalytic subunit and variable regulatory B subunit. TTK encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송 정보
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