Thermo Fisher Scientific MEF2C Monoclonal Antibody (OTI2E2), TrueMAB

Applications and Tested Dilution

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

MEF2C is a transcription activator that binds specifically to the MEF2 element in regulatory regions of many muscle-specific genes. It controls cardiac morphogenesis and myogenesis and is involved in vascular development.
It plays an essential role in hippocampal-dependent learning and memory by regulating synaptic transmission and neuronal development.
MEF2C is also crucial for megakaryocyte and platelet development, B-cell survival, and proliferation. Isoforms 3 and 4, lacking the repressor domain, are more active than isoforms 1 and 2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.