Thermo Fisher Scientific Phospho-PLCg1 (Tyr783) Recombinant Rabbit Monoclonal Antibody (PLCG1Y783-C4)
PLCγ1 Tyr783 인산화 상태를 특이적으로 검출하는 재조합 토끼 단클론 항체로, 인간 및 생쥐 시료에 반응합니다. Flow Cytometry 등 다양한 응용에 적합하며, 고순도 Protein A/G 정제 방식으로 제조되었습니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific Phospho-PLCγ1 (Tyr783) Recombinant Rabbit Monoclonal Antibody (PLCG1Y783-C4)
Applications
- Flow Cytometry (Flow)
Tested Dilution: 1–1,000 ng/mL
Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PLCG1Y783-C4 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Tyr783 of human phospho PLCγ1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 50% glycerol, 0.10% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897233 |
Additional Formats
Target Information
The mammalian Phospholipase Cγ (PLCγ) family includes two closely related proteins, PLCγ1 and PLCγ2. These isozymes share core structural domains and possess a unique array of additional domains, including one PH domain, two SH2 domains, and one SH3 domain.
Upon extracellular stimulation (e.g., hormones and growth factors), receptor tyrosine kinases (RTKs) phosphorylate and activate PLCγ. Activated PLCγ catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2), producing the second messengers inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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