Thermo Fisher Scientific Phospho-PLCg1 (Tyr783) Recombinant Rabbit Monoclonal Antibody (PLCG1Y783-C4), APC
APC 형광으로 표지된 재조합 Rabbit Monoclonal 항체로, 인간 및 생쥐 PLCγ1 Tyr783 인산화 형태를 검출. Flow Cytometry에 적합하며, 높은 특이성과 안정성을 제공. 연구용으로만 사용 가능.
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Thermo Fisher Scientific Phospho-PLCγ1 (Tyr783) Recombinant Rabbit Monoclonal Antibody (PLCG1Y783-C4), APC
Applications
- Flow Cytometry (Flow)
Tested Dilution: 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PLCG1Y783-C4 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Tyr783 of human phospho PLCγ1 |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897234 |
Additional Formats:
- Unconjugated (MA5-37026)
- FITC (MA5-37028)
- PE (MA5-37027)
- Custom conjugation available
Target Information
The mammalian Phospholipase Cγ (PLCγ) family includes two closely related proteins, PLCγ1 and PLCγ2. These isozymes share core structural domains and possess unique regions containing an additional PH domain, two SH2 domains, and one SH3 domain. Upon stimulation by hormones or growth factors, receptor tyrosine kinases (RTKs) phosphorylate and activate PLCγ. Activated PLCγ catalyzes hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP₂), generating the second messenger molecules inositol 1,4,5-triphosphate (IP₃) and diacylglycerol (DAG).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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