Thermo Fisher Scientific ZRANB2 Polyclonal Antibody
Human ZRANB2 단백질을 인식하는 Rabbit Polyclonal 항체로, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며 PBS와 글리세롤 용액 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관이 권장됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ZRANB2. Recombinant protein control fragment (Product # RP-101663) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2791330 |
Product Specific Information
Immunogen sequence:
TKNFRVSDGD WICPDKKCGN VNFARRTSCN RCGREKTTEA KMMKAGGTEI GKTLAEKSRG LFSANDWQCK TCSNVNWARR S
Target Information
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression.
ZNF265 (Zinc finger protein 265), also known as ZRANB2 (Zinc finger Ran-binding domain-containing protein 2), ZIS, ZIS1 or ZIS2, is a 330 amino acid protein belonging to the ZRANB2 family. Localized to the nucleus, ZNF265 functions as a splicing factor responsible for alternatively splicing Tra-2 beta transcripts and may interfere with constitutive 5′-splice selection.
ZNF265 contains two RanBP2-type zinc fingers mediating RNA-binding activity. Two isoforms, ZIS-1 and ZIS-2, are expressed due to alternative splicing events. Upon DNA damage, ZIS-2 may be phosphorylated by ATM or ATR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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