Thermo Fisher Scientific FBXL8 Polyclonal Antibody
FBXL8 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체입니다. Western blot 및 IHC(P)에서 검증되었으며, 인간, 마우스, 랫트에 반응합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 완충액 형태로 제공됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FBXL8. Recombinant protein control fragment (Product #RP-97595) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641539 |
Product Specific Information
Immunogen sequence:
SHAILEALAA PDRAPFALLA LRCACPEDAR ASPLPNEAWV ALRRRHPGLA VELELEPALP AESVTRVLQP AVPVAALRLN LSGDTVGPVR FAAHHYAATL
Highest antigen sequence identity to the following orthologs:
- Mouse: 81%
- Rat: 79%
Target Information
This gene encodes a member of the F-box protein family characterized by an approximately 40 amino acid motif, the F-box. These proteins form part of the SCF (SKP1-cullin-F-box) ubiquitin ligase complex, which functions in phosphorylation-dependent ubiquitination.
F-box proteins are divided into three classes:
- Fbws (containing WD-40 domains)
- Fbls (containing leucine-rich repeats)
- Fbxs (containing other protein-protein interaction modules or no recognizable motifs)
The protein encoded by this gene belongs to the Fbls class and shares 78% sequence identity with the mouse protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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